EpiDestiny develops non-toxic drugs that inhibit epigenetic molecular targets that cancers require for self-replication (cancer ‘stem’ cells) while sparing the normal stem cells vital to health and a normal life-span.
Cancer therapy conventionally follows a
search-and-destroy paradigm, with its attendant collateral damage/toxicity yet frequent poor outcomes, because there was insufficient understanding to permit a
healing-and-repair approach. We now understand that cancer is caused by aberrant turning ‘off’ (repressing) of specialized cell-fate programs by ‘off’ (epigenetic repressing) enzymes. Inhibiting these enzymes resumes cancer cell journeys into cells focused on specialized functions instead of indefinite replication - unstuck and no longer “spinning their wheels” – this non-toxic heal/repair treatment succeeds even in cancers that lack cell-suicide programs and resist chemotherapy and radiation. EpiDestiny owns, develops, and evaluates novel drugs needed to inhibit these enzymes without off-target effects and toxicities.
EpiDestiny is founded on the principle that good science can and should translate into highly effective yet non-toxic treatments, accessible even to patients in low-income countries. We seek strategic partnerships needed for efficient clinical execution and worldwide commercialization.
We are a clinical-stage biopharmaceutical company. Our non-cytotoxic epigenetic drugs leverage the master transcription factor content of diseased cells to restore functional, healthy states, per the Hippocratic dictum “Natural forces within us are the true healers of disease”.
We have already generated clinical proof-of-principle that
We are a clinical-stage biopharmaceutical company. Our non-cytotoxic epigenetic drugs leverage the master transcription factor content of diseased cells to restore functional, healthy states, per the Hippocratic dictum “Natural forces within us are the true healers of disease”.
We have already generated clinical proof-of-principle that our science can and does translate into non-toxic, highly effective clinical treatment for severe non-malignant as well as malignant diseases.
EpiDestiny was founded in 2015 by Yogen Saunthararajah. As a physician-founded company, our driving principle is using science to meet severe unmet clinical needs, in a way that is kind and cost-effective, and without killing cells (cytotoxicity), since preservation of normal dividing cells is essential to health and a normal life-span.
Our first drug: EPI01
is an orally available,
non-toxic, timed-release combination small molecule product.
EPI01 to treat Sickle Cell Disease and β-thalassemia is being developed in partnership with Novo Nordisk (Research Collaboration Agreement).
EpiDestiny is developing EPI01 and other noncytotoxic epigenetic therapeutics to treat c
Our first drug: EPI01
is an orally available,
non-toxic, timed-release combination small molecule product.
EPI01 to treat Sickle Cell Disease and β-thalassemia is being developed in partnership with Novo Nordisk (Research Collaboration Agreement).
EpiDestiny is developing EPI01 and other noncytotoxic epigenetic therapeutics to treat chemo- and radiation-resistant liquid and solid tumor malignancies.
Please reach out to us with any requests.
Feel free to contact {henry@epidlife.com}.
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Saturday - Sunday: Closed